Doctor Yiwei Shi pioneers FDA-approved treatment Leosin for rare disease inspired by son Leo

During a recent meeting of the New York Legislature, Senator Palumbo highlighted the remarkable achievements of Dr. Yiwei Shi, who has been named the 2025 Woman of Distinction from his district. Dr. Shi's journey began with a personal motivation—her son Leo, who suffers from an ultra-rare neurodevelopmental disease.

Through her dedication and research efforts, Dr. Shi successfully developed Leosin, an FDA-approved treatment specifically designed for Leo's condition. This groundbreaking drug not only represents a significant medical advancement but also showcases Dr. Shi's commitment to improving the lives of children facing similar challenges.

In addition to her work on Leosin, Dr. Shi founded the TNPO 2 Foundation, which aims to support children with rare diseases. Her ongoing efforts continue to inspire others in the medical community and beyond, highlighting the importance of advocacy and innovation in healthcare.

The recognition of Dr. Shi as Woman of Distinction underscores the impact of individual contributions to the community and the vital role of research in addressing rare diseases. As the legislature moves forward, her story serves as a reminder of the power of perseverance and the importance of supporting families affected by rare medical conditions.